Which popular weight-loss ingredients are worth paying attention to both domestically and internationally?

In 2026, a sample study covering 300 million people worldwide was published in the authoritative medical journal The Lancet.In 2026, a sample study covering 300 million people worldwide was published in the authoritative medical journal The Lancet. The study revealed that by 2025, the number of global obese individuals had exceeded 1.1 billion. The study revealed that by 2025, the number of global obese individuals had exceeded 1.1 billion. In the face of this serious situation, weight management has become a core issue for the overall health of the entire population. In the face of this serious situation, weight management has become a core issue for the overall health of the entire population.

The large number of obese people has given rise to a huge weight loss industry.T According to Grand View Research, the global weight loss supplement market was approximately 33.he large number of obese people has given rise to a huge weight loss industry. According to Grand View Research, the global weight loss supplement market was approximately 33.14 billion US dollars in 2025, and is expected to grow to 71.14 billion US dollars in 2025, and is expected to grow to 71.59 billion US dollars by 2030, with a compound annual growth rate of 14.59 billion US dollars by 2030, with a compound annual growth rate of 14.17% from 2025 to 2030.17% from 2025 to 2030.

This article will review the notable weight-loss ingredients both domestically and internationally. Using the keywords "weight loss" and "help control body fat", 529 health food registration information was retrieved from the special food information query platform. The main ingredients include lotus leaf (237 entries), kudzu root (190 entries), L-carnitine (197 entries), jujube (107 entries), alisma (127 entries), and poria (82 entries), etc.

Lotus Leaf: Lotus leaf is the dried leaf of the plant Nelumbo nucifera in the Nymphaeaceae family. In 2002, the former Ministry of Health included it in the "List of Items Both as Food and Medicine", making it one of the first substances in China that are both food and medicine. It is neutral in nature and has a bitter taste, and it belongs to the meridians of the liver, spleen, and stomach. It has the functions of clearing heat and eliminating dampness, promoting the rise of clear yang, and cooling blood and stopping bleeding.
In "Compendium of Materia Medica", it was recorded that "Taking lotus leaf leads to weight loss". Modern research has found that lotus leaf contains various active components such as alkaloids (lotus leaf alkaloid, original lotus leaf alkaloid, etc.), flavonoids (quercetin, isorhamnetin, etc.), polysaccharides, and organic acids. Among them, lotus leaf alkaloid has particularly prominent effects in lipid regulation and weight loss. Studies have shown that lotus leaf alkaloid mainly exerts its weight loss effect by inhibiting the activity of lipase, regulating the expression of genes related to lipid metabolism, and promoting energy consumption.
Currently, lotus leaf is widely used in products such as lotus leaf tea and compound solid beverages. Common combination ideas include "lotus leaf + kudzu root", "lotus leaf + jujube", "lotus leaf + dried tangerine peel", etc.

L-carnitine: L-carnitine, also known as L-carnine, is a type of amino acid-like substance with the chemical formula C7H15NO3. The human body can synthesize L-carnitine in organs such as the liver, kidneys, and brain, and it can also be obtained from meat foods.
In 1958, Fritz et al. first confirmed that L-carnitine plays an important role in the oxidation of long-chain fatty acids in muscle and heart tissues, can increase the rate of β-oxidation of fat, and accelerate the consumption of fat by mitochondria. In addition, L-carnitine can transport fatty acids from the cytoplasm to the mitochondria by binding to them, thereby providing energy support. Tong Ren Tang brand Qingya Pi contains 20g of L-carnitine per 100g, and also adds calcium pyruvate, lotus leaf extract, and skimmia extract, and has a weight loss function.

Alisma: Alisma is the dried tuber of the plant Alisma orientale (Sam.) Juzep. or Alisma plantago-aquatica Linn., which has a yellowish-white cross-section with numerous small pores.Alisma: Alisma is the dried tuber of the plant Alisma orientale (Sam.) Juzep. Alisma can eliminate heat, clear turbidity, and lower lipid levels by promoting diuresis and diaphoresis, and improving the accumulation of water and dampness caused by spleen deficiency.

In recent years, weight loss has been a popular application area in the Japanese market. According to the statistics from Food Research Hub, as of June 22, 2026, the Japan Consumer Agency has reported a total of 106 functional foods claiming to have fat-reducing effects. In the Japanese market, functional foods can claim a wide range of fat-reducing benefits, such as reducing visceral fat, subcutaneous fat, and inhibiting fat absorption and promoting metabolism.

Among these 106 functional foods, the raw materials with high usage frequency include ellagic acid, poly-methoxylated flavonoids (black ginger), and 3-(4-hydroxy-3-methoxyphenyl)propionic acid (HMPA). Medium-chain fatty acids (octanoic acid, decanoic acid), poorly digestible dextrin (dietary fiber), alokutinose, catechins (including gallic acid-type catechins), proanthocyanidins (from apples and acacia bark), isoflavones (from kudzu flowers), hydroxycitric acid (HCA), etc.

Ellagic acid: Ellagic acid belongs to the tannin-type polyphenols of the ellagitannin class. It is a dimer derivative of gallic acid and is widely present in various fruits (such as pomegranates, persimmons, raspberries, and peaches), oilseed kernels (such as walnuts and almonds), and vegetables.
Ellagic acid can exert various fat-reducing effects. Animal experiments have shown that ellagic acid can dose-dependently alleviate lipid accumulation in mice and zebrafish induced by high-fat diet, reduce the levels of pro-inflammatory factors IL-6 and TNF-α in the serum of mice, and improve liver steatosis. Cell experiments have confirmed that ellagic acid can stably bind to PPARγ and inhibit the accumulation of lipid in liver cells.
The product "Eraguic Acid's Power" launched by Third Knowledge Corporation adds ellagic acid derived from pomegranates. This product can reduce body fat, blood triglycerides, weight, waist circumference, and visceral fat in obese individuals, and help improve a higher BMI value.
Poly-methoxyflavonoids (black ginger): Black ginger, also known as small-flowered mountain ginger or Thai ginseng, is a medicinal herb native to Southeast Asia. It has attracted attention due to its rich content of methoxyflavonoid bioactive substances. Current research has confirmed that these active components can regulate metabolic pathways in the body, accelerate fat breakdown, and reduce lipid accumulation, achieving the effect of assisting weight management.

In recent years, black ginger polyhydroxyflavones have performed exceptionally well in the functional food market in Japan.In recent years, black ginger polyhydroxyflavones have performed exceptionally well in the functional food market in Japan. They are the star ingredients in weight loss products and have consistently ranked among the top weight loss ingredients in Japan. They are the star ingredients in weight loss products and have consistently ranked among the top weight loss ingredients in Japan. Currently, well-known Japanese brands such as Morinaga and FANCL have all launched functional foods with this ingredient as the core.
The company Nishinippon Pharmaceutical Co., Ltd. Currently, well-known Japanese brands such as Morinaga and FANCL have all launched functional foods with this ingredient as the core.
The company Nishinippon Pharmaceutical Co., Ltd. has added polyhydroxyflavones derived from black ginger to their product "Naisi Help a", which has the effect of reducing visceral fat in people with high BMI. has added polyhydroxyflavones derived from black ginger to their product "Naisi Help a", which has the effect of reducing visceral fat in people with high BMI.

Allohexose: Allohexose, also known as D-allohexose, is a rare natural sugar. It is a hexose ketose and is present in small amounts in figs, kiwis, raisins, wheat, maple syrup, and honey. In 2011, the US FDA first certified its safety and allowed it to be used as a dietary supplement and food ingredient. Additionally, D-allohexose has received regulatory approval in multiple countries such as the United States, Japan, South Korea, Canada, and Australia. In July 2025, D-allohexose was approved by the National Health Commission of China, officially becoming a new food raw material.
In 2023, a clinical trial demonstrated that 26 overweight or obese adults with type 2 diabetes who took 2 portions of diabetes-specific oral nutritional supplements containing D-allohexose every morning for 8 consecutive weeks showed that D-allohexose significantly improved the blood sugar indicators of the subjects and significantly reduced weight, BMI, and waist circumference.
In 2021, D-allohexose was first used in functional labeled foods in Japan, marking the beginning of its application in fat reduction products. For example, the company Japanese Yakuhin launched the powder product Miracle Sugara, which added D-allohexose and had the function of enhancing energy metabolism and fat burning during daily activities (rest or daily activities).

Rosefruit Silver Ligustrazine: The rosefruit is the fruit of the Rosa canina plant in the Rosaceae family, and has a long history of consumption and medicinal use in Europe and America.Rosefruit Silver Ligustrazine: The rosefruit is the fruit of the Rosa canina plant in the Rosaceae family, and has a long history of consumption and medicinal use in Europe and America. Due to its high content of vitamin C and various polyphenols, it has long been considered to have excellent skin-firming effects and is also known as the "super fruit". Due to its high content of vitamin C and various polyphenols, it has long been considered to have excellent skin-firming effects and is also known as the "super fruit". Silver ligustrazine is a type of flavonoid glycoside compound and is one of the important active components of rosefruit. Silver ligustrazine is a type of flavonoid glycoside compound and is one of the important active components of rosefruit. Clinical human experiments have shown that daily use of 100mg of rosefruit extract containing silver ligustrazine can significantly achieve weight loss, reduction in total fat area, etc. Clinical human experiments have shown that daily use of 100mg of rosefruit extract containing silver ligustrazine can significantly achieve weight loss, reduction in total fat area, etc. In addition, silver ligustrazine also has the potential to lower uric acid levels, and can reduce uric acid levels in plasma and liver.
In addition, silver ligustrazine also has the potential to lower uric acid levels, and can reduce uric acid levels in plasma and liver.
The black vinegar "Mozuku" launched by Kaineruo Marine Products Co., Ltd.The black vinegar "Mozuk" launched by Kaineruo Marine Products Co., Ltd. is different from common beverages and capsule products. is different from common beverages and capsule products. It is a seaweed-flavored dish that has added rosefruit silver ligustrazine, which helps reduce visceral fat in people with high BMI.

The popular fat-reducing ingredients in the US market mainly consist of apple cider vinegar, caffeine, green tea extract, green coffee extract, L-carnitine, white bean extract, and conjugated linoleic acid. They are often combined with various dietary fibers and are the standard formula for Amazon best-selling products. It is worth noting that due to increasingly strict regulatory reviews and the growing interest in GLP-1 drugs, probiotics, berberine, MCT (medium-chain triglycerides), and orange peel extract have become new popular ingredients.

Apple cider vinegar: Apple cider vinegar is made from apple juice. First, yeast and bacteria convert fructose in the apple juice into ethanol, and then ethanol is oxidized into acetic acid.Apple cider vinegar: Apple cider vinegar is made from apple juice. First, yeast and bacteria convert fructose in the apple juice into ethanol, and then ethanol is oxidized into acetic acid. In addition, it also contains malic acid, citric acid, a small amount of vitamins (such as B vitamins, C vitamins), minerals (potassium, calcium, magnesium), and soluble dietary fiber (pectin).
In addition, it also contains malic acid, citric acid, a small amount of vitamins (such as B vitamins, C vitamins), minerals (potassium, calcium, magnesium), and soluble dietary fiber (pectin).
Apple cider vinegar mainly prevents obesity through mechanisms such as slowing down gastric emptying and enhancing satiety, activating AMP-activated protein kinase, and regulating the intestinal microbial flora. Its product forms are diverse, and gummy candies are the most representative.Apple cider vinegar mainly prevents obesity through mechanisms such as slowing down gastric emptying and enhancing satiety, activating AMP-activated protein kinase, and regulating the intestinal microbial flora. Its product forms are diverse, and soft candies are the most representative.

The SPINS data on probiotics for weight management on Amazon shows that the sales of probiotics on Amazon increased by 84% in 2025, driven by the rise of GLP-1 drugs.The SPINS data on probiotics for weight management on Amazon shows that the sales of probiotics on Amazon increased by 84% in 2025, driven by the rise of GLP-1 drugs. In 2001, the Food and Agriculture Organization of the United Nations (FAO) and the World Health Organization (WHO) defined probiotics as "live microorganisms that, when consumed in sufficient quantities, are beneficial to the host's health".
 In 2001, the Food and Agriculture Organization of the United Nations (FAO) and the World Health Organization (WHO) defined probiotics as "live microorganisms that, when consumed in sufficient quantities, are beneficial to the host's health"Currently, classic strains such as Lactobacillus rhamnosus B420, Lactobacillus casei BNR17, and Lactobacillus cecatum CECT 8145 have obtained the US GRAS certification, further verifying their safety and making them suitable for use in common foods and dietary supplements.
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Currently, classic strains such as Lactobacillus rhamnosus B420, Lactobacillus casei BNR17, and Lactobacillus cecatum CECT 8145 have obtained the US GRAS certification, further verifying their safety and making them suitable for use in common foods and dietary supplements.
SkinnyFit's a natural GLP-1 probiotic supplement contains infant bifidobacteria, Akermania, and butyric acid bacteria, claiming to help balance intestinal bacteria, support digestion, metabolism, and weight management.SkinnyFit's a natural GLP-1 probiotic supplement contains infant bifidobacteria, Akermania, and butyric acid bacteria, claiming to help balance intestinal bacteria, support digestion, metabolism, and weight management.

Berberine: Berberine (also known as Huanglianzi) is a benzyl tetraisoquinoline alkaloid, a yellow needle-like crystalline compound, which can be obtained through natural plant extraction or artificial synthesis. It was first discovered by Buchner and Herberger in 1830.
The SPINS data shows that the sales of berberine products increased by 92.6% in 2024. With the promotion of TikTok influencers, this raw material is regarded as a natural alternative to the weight loss prescription drug Ozempic (somatropin), which is an FDA-approved prescription drug for type 2 diabetes for blood sugar control and weight management.
A 2022 meta-analysis, which combined 18 studies on weight and 23 studies on body mass index (BMI), showed that the weight and BMI of the subjects taking berberine decreased significantly.
A capsule from LifeSeasons contains 1000 milligrams of berberine per capsule and claims to help balance blood sugar and lipid levels.