Who is the “King of Weight Loss”? ——Inventory of the "weight loss effects" of ten types of weight loss powders

There is an inseparable link between obesity and complications, and they often go hand in hand and reinforce each other. In China, the prevalence of diabetes is approximately 12%, and 34% of patients are also overweight or obese. Effective weight loss can not only improve the patient's metabolic status, but also reduce the risk of complications and improve the quality of life.
In recent years, with the development and application of weight loss drugs, the field of obesity treatment has ushered in a revolution, because these drugs have significant weight loss effects and have brought new treatment options to obese patients. So, what is the weight loss effect of these drugs? This article takes stock one by one.

There are many kinds of weight loss and slimming powders on the market, and different types of weight loss and slimming powders also have different weight loss effects. Next, I will give you a detailed inventory of the "weight loss effects" of ten common types of weight loss powders. The first is dietary fiber powder, which is rich in dietary fiber. After entering the human body, it can increase the feeling of fullness and reduce the intake of other high-calorie foods. At the same time, dietary fiber can also promote intestinal peristalsis, speed up metabolism, and help eliminate toxins and excess waste from the body. For people who are mildly obese and have slow intestinal peristalsis, they can see a certain weight loss effect if they continue to take it for a period of time.

There are also meal replacement powders. This type of weight loss powder is usually more comprehensive in nutrition and can control caloric intake while providing the basic nutrients needed by the body. After many people use meal replacement powder to replace some staple foods, the overall calorie gap gradually forms, thereby achieving weight loss. However, relying solely on meal replacement powder for a long time may lead to nutritional imbalance, so it needs to be used with other foods.
L-carnitine powder is also one that has attracted much attention. Its main function is to help fat be better converted into energy during exercise and improve the efficiency of fat burning during exercise. If combined with regular and appropriate intensity exercise, L-carnitine powder can make the weight loss effect more obvious. But if you don’t exercise and rely solely on it to lose weight, the effect may not be ideal.

Green tea powder is rich in catechins and other ingredients, which have antioxidant effects. It can also increase metabolism to a certain extent and promote fat oxidation and decomposition. Drinking an appropriate amount of green tea powder every day, combined with a healthy diet and moderate exercise, is a good choice for people who want to lose weight slowly.
Probiotic powder focuses on regulating the balance of intestinal flora. When the number of beneficial bacteria in the intestines increases, intestinal function is improved, and digestion and absorption capabilities will be healthier. This helps reduce the accumulation of fat in the body, and has a better effect on improving obesity caused by intestinal flora imbalance.

Collagen powder is also unique in weight loss. It increases skin elasticity and prevents skin sagging during weight loss. At the same time, appropriate supplementation of collagen can maintain muscle mass, because the higher the muscle content, the higher the basal metabolic rate, which is more conducive to continuous calorie consumption and long-term weight loss.

Garcinia cambogia extract powder contains ingredients such as hydroxycitric acid, which can inhibit fat synthesis and reduce appetite. Some studies have shown that Garcinia Cambogia Extract Powder can be helpful for weight control, but the specific effects may vary depending on individual physiques.

Orlistat powder is an over-the-counter weight loss drug. Its main mechanism of action is to inhibit lipase activity in the gastrointestinal tract, thereby reducing the absorption of fat in food and allowing fat to be directly excreted from the body. Generally speaking, when a normal diet contains a certain amount of fat, taking orlistat powder can prevent a considerable part of the fat from being absorbed by the body. For some obese people who usually consume more fat in their diet, using orlistat powder can significantly reduce their caloric intake. However, it may also cause some side effects, such as symptoms of gastrointestinal discomfort, such as oily spots, increased gastrointestinal flatulence, stool urgency, fatty (oily) stools, steatorrhea, increased stool frequency, and fecal incontinence. Moreover, it has a certain impact on nutrients and may reduce the absorption of fat-soluble vitamins (such as vitamins A, D, E, K) and beta-carotene. Therefore, these vitamins need to be supplemented appropriately while taking orlistat powder. Overall, orlistat powder, when used rationally, can achieve a good weight loss effect for obese people with targeted needs, but it is also necessary to pay attention to its side effects and impact on nutrition.

Other oral preparations - representative drug "Orforglipron"
In order to overcome the limitation of low bioavailability of peptide drugs, the new drug Orforglipron was gradually developed. Orforglipron is an oral small molecule GLP-1 receptor partial agonist that also needs to be taken daily, but it is not affected by food and other drugs and can be taken before or after meals. In the completed phase II clinical study, the weight loss achieved by using Orforglipron for half a year reached 10.1 kilograms. Currently, the drug is in the application stage for Phase III clinical trials in China.

Finally, there is sibutramine powder, which is a central nervous system neurotransmitter reuptake inhibitor. Specifically, it can inhibit the reuptake of serotonin (5-HT), norepinephrine, and dopamine by neurons. When these neurotransmitters are at high concentrations in the brain, they enhance the satiety signal, thereby reducing your desire to eat.
The user will feel a significant sense of fullness and naturally reduce their food intake ("dieting").
Weight loss has multiple benefits for obese individuals, which are not limited to improving blood sugar control, but also include overall health improvement. Here are some of the main benefits of weight loss for obese individuals:

➤ Improve blood sugar control: Losing weight can increase the body's sensitivity to insulin, thereby helping to lower blood sugar levels.
➤ Reduce the risk of cardiovascular disease: Weight loss helps reduce the risk of hypertension, hyperlipidemia and cardiovascular disease, which are common complications of diabetes.
➤ Improve liver health: Weight loss helps reduce the risk of fatty liver disease, which is related to diabetes and obesity.
➤ Improving quality of life: Losing weight can increase energy levels, improve sleep, and enhance overall quality of life.
➤ Improve breathing: For diabetes patients with obstructive sleep apnea, weight loss can significantly improve the quality of breathing and sleep.
➤ Improving fertility: For women with diabetes who want to get pregnant, weight loss can improve fertility and reduce the risk of pregnancy complications.
➤ Enhance physical activity ability: With weight loss, it becomes easier to engage in physical activity, which further contributes to weight management and health.
➤ Psychological health benefits: Losing weight can also increase self-confidence and self-esteem, and reduce the psychological pressure associated with obesity.
➤ Economic benefits: In the long run, weight loss may reduce healthcare costs associated with obesity by preventing complications and reducing medication use.